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6 Types of Medication for Back Pain

There is no single best medicine for back pain. For short-term back pain, over-the-counter NSAIDs such as ibuprofen or naproxen, or acetaminophen (Tylenol), are usually tried first; prescription options include muscle relaxants, nerve pain medicines, certain antidepressants and, for short periods, opioids.

3 min read

Back pain is a common problem seen throughout the world. Acute back pain lasts less than four weeks, subacute back pain lasts four to twelve weeks, and chronic back pain lasts longer than twelve weeks. Some injuries may require no medication and others may require medication. Treatment plans are tailored to each individual and no two people will be identical in their treatment.

Over-the-Counter Pain Relievers

Over-the-counter pain relievers may be used for acute back pain. These include NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen and naproxen. These medications are helpful but need to be taken with care. Follow the directions to ensure safe ingestion of these medications. Another over-the-counter option is acetaminophen (Tylenol). It is not an NSAID, but it can help patients with acute back pain. If these medications are not working, talk to a healthcare professional about other options.

Muscle Relaxants

Muscle relaxants can be used for patients who are not getting pain relief from over-the-counter medications. Muscle relaxants can help reduce skeletal muscle spasms, relieve pain, and improve mobility in the affected muscles. [1] Some common muscle relaxers are cyclobenzaprine, methocarbamol, and baclofen. Muscle relaxers may cause drowsiness, dizziness, dry mouth, or depression. When not taken properly these medications can be lethal.

Topical Pain Relievers

Topical pain relievers can be helpful depending on the pain you are experiencing. Common topical options include Icy Hot, Gold Bond, lidocaine patches, and diclofenac. [1] Before using a topical pain reliever for the first time, test a small amount on a small area of skin to make sure you are not allergic to it. Some of these medications may cause allergic reactions and it is much easier to treat a small surface area than a large area like the back. If the over the counter topical pain relievers are not working there are prescription level topical pain relievers your physician may be able to prescribe for you.

Opioids

The strongest medications that may be used for back pain are opioids. These include oxycodone and hydrocodone. They are highly addictive and have been proven not to work well for chronic back pain. [2] These medications are commonly used after surgery to help reduce pain. Opioid prescriptions are typically kept short to avoid dependence.

Anti-Epileptic Drugs

Anti-epileptic drugs may be used to help calm nerve pain. Nerve pain can be treated with gabapentin, carbamazepine, topiramate, and others. [3] These medications work by changing how easily and how often nerve endings fire. These medications have side effects like drowsiness, dizziness, constipation, nausea, confusion, and sometimes loss of balance.

Antidepressants

The last type of pain medication that may be used for your back pain is antidepressants. Some antidepressants have been shown to relieve chronic back pain. [2] Medications shown to do this include duloxetine and amitriptyline. These medications work by increasing chemicals in the back that have been shown to reduce pain signals. They may take several days before you begin to see positive results with these medications.

Conclusion

No matter which medication you are taking for your back pain, it is very important to follow the directions. Medications are generally safe when following instructions. If you experience side effects from these medications, tell your healthcare provider. Some people may need medications to treat their back pain and other people may be able to manage with other forms of therapy. Find a balance that works for you.

Sources

1. Falla, K. (2019, November 4). Medications for Back Pain and Neck Pain. Spine-health. Retrieved June 17, 2022, from https://www.spine-health.com/treatment/pain-medication/medications-back-pain-and-neck-pain

2. Mayo Foundation for Medical Education and Research. (2020, August 21). Back Pain. Mayo Clinic. Retrieved June 17, 2022, from

https://www.mayoclinic.org/diseases-conditions/back-pain/diagnosis-treatment/drc-20369911

3. Jacques, E. (2022, February 25). Anticonvulsants may be Able to Help Your Chronic Pain. Verywell Health. Retrieved June 17, 2022, from https://www.verywellhealth.com/anti-seizure-medications-for-chronic-pain-2564494

Frequently asked questions about medications for back pain.

What is the best medicine for lower back pain?

There is no single best medicine for lower back pain; the right choice depends on the type of pain and how long it has lasted. For short-term (acute) back pain, over-the-counter NSAIDs such as ibuprofen or naproxen, or acetaminophen, are common first choices. If those don’t help, a doctor may prescribe a muscle relaxant, a prescription topical or another option. Always follow the directions.

What do doctors prescribe for back pain?

When over-the-counter medicines aren’t enough, doctors may prescribe muscle relaxants (such as cyclobenzaprine, methocarbamol or baclofen), prescription-strength topical pain relievers, anti-epileptic drugs such as gabapentin for nerve pain, or antidepressants such as duloxetine or amitriptyline for chronic back pain. Opioids are kept to short periods, most often after surgery.

What is the best medication for chronic back pain?

For chronic back pain, which lasts longer than 12 weeks, some antidepressants, such as duloxetine and amitriptyline, have been shown to relieve pain, and anti-epileptic drugs such as gabapentin can calm nerve pain. Opioids have been shown not to work well for chronic back pain and are highly addictive. Many people manage chronic back pain with a mix of medication and other therapies.

What is the best muscle relaxer for back pain?

No one muscle relaxer is best for everyone. Common choices for back pain are cyclobenzaprine, methocarbamol and baclofen, usually prescribed when over-the-counter pain relievers haven’t helped. They can ease muscle spasms and pain and improve mobility, but may cause drowsiness, dizziness, dry mouth or depression. Take them exactly as prescribed: taken incorrectly, they can be dangerous.

Is gabapentin good for back pain?

Gabapentin can help back pain that comes from irritated nerves. It is an anti-epileptic drug that calms nerve pain by changing how easily and how often nerve endings fire. Side effects can include drowsiness, dizziness, constipation, nausea, confusion and sometimes loss of balance. A doctor can tell you whether your pain is nerve pain and whether gabapentin fits.

Is tramadol good for back pain?

Tramadol is an opioid pain medicine. Opioids, which also include hydrocodone and oxycodone, are the strongest medicines used for back pain, but they are highly addictive and have been shown not to work well for chronic back pain. They are mostly used for a short time, such as after surgery, and prescriptions are kept short to avoid dependence.

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